Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340889 | 1.00 | KMT2A (0.52) | KMT2AMEN1SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL7339076 | 0.84 | SMN1; SMN2 (0.60) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7339630 | 0.84 | MEN1 (0.51) | KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL7341981 | 0.83 | EGFR (0.66) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7341979 | 0.83 | EGFR (0.66) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7330954 | 0.81 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7331661 | 0.80 | ALDH1A1 (0.57) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7328819 | 0.78 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL7339865 | 0.78 | KMT2A (0.55) | KMT2AMEN1SMN1; SMN2MTNR1BMAPT | |
| SCHEMBL7341015 | 0.78 | TSHR (0.58) | KMT2AMEN1SMN1; SMN2PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475531-B1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | ASAHI CHEMICAL IND (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0475531-A1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-03-18 | — | — | EP | disclosed |