Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.66 |
| ▸ | MMP1 | P03956 | 9/20 | 0.64 |
| ▸ | MMP2 | P08253 | 9/20 | 0.64 |
| ▸ | MMP9 | P14780 | 9/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | TOP2A | P11388 | 2/20 | 0.55 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341979 | 1.00 | EGFR (0.66) | EGFRMMP1MMP2MMP9MAOA | |
| SCHEMBL7340889 | 0.83 | KMT2A (0.52) | EGFRMMP1MMP2MMP9MEN1 | |
| SCHEMBL7340885 | 0.83 | KMT2A (0.52) | EGFRMMP1MMP2MMP9MEN1 | |
| SCHEMBL7330717 | 0.82 | KMT2A (0.46) | EGFRMMP1MMP2MMP9MEN1 | |
| SCHEMBL7330713 | 0.82 | KMT2A (0.46) | EGFRMMP1MMP2MMP9MEN1 | |
| SCHEMBL7339630 | 0.80 | MEN1 (0.51) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1996366 | 0.79 | MMP1 (0.72) | EGFRMMP1MMP2MMP9MAOA | |
| SCHEMBL1996368 | 0.79 | MMP1 (0.72) | EGFRMMP1MMP2MMP9MAOA | |
| N-(4-Chlorophenyl)Cinnamamide SCHEMBL8684664 | 0.79 | MMP1 (1.00) | EGFRMMP1MMP2MMP9MAOA | |
| N-(4-Chlorophenyl)Cinnamamide SCHEMBL8684658 | 0.79 | MMP1 (1.00) | EGFRMMP1MMP2MMP9MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475531-B1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | ASAHI CHEMICAL IND (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0475531-A1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-03-18 | — | — | EP | disclosed |