Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338260 | 0.84 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL7348705 | 0.76 | CYP1A2 (0.39) | CRHR1ADRA1AUBE2MDCUN1D1 | |
| SCHEMBL12744415 | 0.73 | TSHR (0.43) | CNR1TP53NPC1RAB9ASLC6A2 | |
| SCHEMBL7341248 | 0.73 | CYP1A2 (0.38) | CRHR1LMNAKDM4EKCNH2UBE2M | |
| SCHEMBL7348299 | 0.71 | KMT2A (0.48) | RAB9AUBE2MDCUN1D1 | |
| SCHEMBL9909358 | 0.66 | NPC1 (0.48) | CNR1TP53NPC1RAB9ASLC6A4 | |
| SCHEMBL7339944 | 0.66 | CYP1A2 (0.36) | LMNAHRH1KCNH2 | |
| SCHEMBL4105828 | 0.63 | MEN1 (0.37) | — | |
| SCHEMBL23902086 | 0.63 | MEN1 (0.39) | — | |
| SCHEMBL23121057 | 0.62 | CYP1A2 (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598962-B1 | Imidazole derivatives as calcium channel blockers | NEUROSEARCH AS (DK) | 1999-02-17 | — | — | EP | claimed |