Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329575 | 0.69 | ELANE (0.38) | ELANE | |
| SCHEMBL7330540 | 0.60 | DAO (0.31) | — | |
| SCHEMBL7332210 | 0.59 | DAO (0.30) | — | |
| SCHEMBL1270333 | 0.58 | LPAR3 (0.46) | — | |
| SCHEMBL2368023 | 0.57 | SORT1 (0.33) | — | |
| SCHEMBL28933243 | 0.57 | LPAR3 (0.45) | — | |
| Methane SCHEMBL7755990 | 0.57 | LPAR3 (0.45) | — | |
| Phosphoric Acid SCHEMBL27874485 | 0.57 | LPAR3 (0.45) | — | |
| SCHEMBL17135346 | 0.56 | ENPP2 (0.39) | — | |
| SCHEMBL19727118 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541168-A | PROTEOLYTIC ENZYME INHIBITORS; DEGENERATIVE DISEASES; RESPIRATORY, SKIN, GENETIC AND GASTROINTESTINAL DISORDERS; ANTIARRTHRITIC AND -INFLAMMATORY AGENTS; GENETIC DISEASES | STERLING WINTHROP INC. (US) | 1996-07-30 | — | — | US | disclosed |
| WO-1996016970-A1 | SUBSTITUTED 2-(PHOSPHINYLOXYMETHYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDES AND COMPOSITIONS AND METHOD OF USE THEREOF | SANOFI WINTHROP, INC. (US) | 1996-06-06 | — | — | WO | disclosed |