Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9479734 | 0.79 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14HDAC6 | |
| SCHEMBL7350991 | 0.72 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14HDAC6 | |
| SCHEMBL24512636 | 0.70 | RHOA (0.48) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL71303 | 0.70 | TSHR (0.69) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL9478869 | 0.69 | MAPT (0.71) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL1930247 | 0.69 | MAPT (0.71) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2742816 | 0.68 | MAPK13 (0.95) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| Diphenylamine SCHEMBL10651863 | 0.68 | MAPT (0.57) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| 4-Phenylamino Benzoic Acid SCHEMBL70190 | 0.68 | MAPK13 (0.72) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL9479471 | 0.68 | MAPK13 (0.72) | MAPK13MAPK12MAPK11MAPK14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |