Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342306 | 0.92 | MEN1 (0.56) | ALDH1A1KDM4ETSHRSMN1; SMN2NPC1 | |
| SCHEMBL7340688 | 0.92 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRSMN1; SMN2NPC1 | |
| SCHEMBL7349167 | 0.89 | RNF4 (0.59) | ALDH1A1KDM4ETSHROPRM1KMT2A | |
| SCHEMBL7342383 | 0.85 | HDAC1 (0.69) | ALDH1A1KDM4ETSHRSMN1; SMN2LTB4R2 | |
| SCHEMBL7339635 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4ETSHRSMN1; SMN2NPC1 | |
| SCHEMBL7339476 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRSMN1; SMN2NPC1 | |
| SCHEMBL7339492 | 0.82 | POLB (0.58) | ALDH1A1KDM4ETSHRSMN1; SMN2OPRM1 | |
| SCHEMBL7349543 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRSMN1; SMN2NPC1 | |
| SCHEMBL7347840 | 0.82 | MAPT (0.50) | ALDH1A1KDM4ETSHROPRM1KMT2A | |
| SCHEMBL14174757 | 0.81 | MEN1 (0.61) | ALDH1A1KDM4ETSHRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |