Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339635 | 0.86 | ALDH1A1 (0.54) | ALDH1A1KDM4ETSHRKMT2AHTR6 | |
| SCHEMBL7349543 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRKMT2AHTR6 | |
| SCHEMBL7341990 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL7341844 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRKMT2AHTR6 | |
| SCHEMBL7342306 | 0.79 | MEN1 (0.56) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL7340688 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7343939 | 0.79 | CACNA2D1 (0.50) | ALDH1A1KDM4ETSHRKMT2AL3MBTL1 | |
| SCHEMBL7349167 | 0.79 | RNF4 (0.59) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL7343019 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRHTR6POLB | |
| SCHEMBL7339492 | 0.77 | POLB (0.58) | ALDH1A1KDM4ETSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |