Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.49 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.48 |
| ▸ | ITGAV | P06756 | 12/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343426 | 0.89 | SUCNR1 (0.53) | ITGB3ITGA2BSUCNR1ITGAV | |
| SCHEMBL6779399 | 0.83 | GPR132 (0.47) | — | |
| SCHEMBL6773807 | 0.81 | ITGB3 (0.48) | ITGB3ITGA2BSUCNR1ITGAV | |
| SCHEMBL6777410 | 0.81 | SUCNR1 (0.54) | ITGB3ITGA2BSUCNR1ITGAV | |
| SCHEMBL27485849 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2BSUCNR1ITGAV | |
| SCHEMBL7832625 | 0.78 | TP53 (0.41) | — | |
| SCHEMBL6782755 | 0.78 | ITGB3 (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL7348665 | 0.77 | ITGB3 (0.48) | ITGB3ITGAV | |
| SCHEMBL7336878 | 0.76 | SUCNR1 (0.47) | ITGB3ITGA2BSUCNR1ITGAV | |
| SCHEMBL7832621 | 0.76 | ITGB3 (0.44) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201454-A | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 1998-12-09 | — | — | CN | claimed |
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | disclosed |