Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.54 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342701 | 1.00 | LTA4H (0.55) | LTA4HSIRT2AURKARPS6KB1HDAC8 | |
| SCHEMBL2367419 | 0.82 | SLC7A5 (0.50) | LTA4HSIRT2AURKARPS6KB1HDAC8 | |
| SCHEMBL7338844 | 0.82 | LTA4H (0.65) | LTA4HLNPEP | |
| SCHEMBL7338836 | 0.82 | LTA4H (0.65) | LTA4HLNPEP | |
| SCHEMBL7339057 | 0.82 | LTA4H (0.65) | LTA4HLNPEP | |
| SCHEMBL15890597 | 0.81 | CYP17A1 (0.52) | LTA4HAURKARPS6KB1 | |
| SCHEMBL12533268 | 0.81 | SIRT2 (0.60) | LTA4HSIRT2ADAMTS4PTPN1PDK1 | |
| SCHEMBL20132198 | 0.80 | SIRT2 (0.59) | LTA4HSIRT2AURKARPS6KB1HDAC8 | |
| SCHEMBL2367233 | 0.79 | SLC7A5 (0.64) | AURKARPS6KB1 | |
| SCHEMBL3050840 | 0.79 | SLC7A5 (0.64) | AURKARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |