Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 13/20 | 0.58 |
| ▸ | PLG | P00747 | 9/20 | 0.58 |
| ▸ | F2 | P00734 | 9/20 | 0.58 |
| ▸ | PLAT | P00750 | 8/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.58 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.58 |
| ▸ | F10 | P00742 | 5/20 | 0.44 |
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 5/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7344307 | 0.92 | PLAU (0.56) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL7336369 | 0.87 | PLAU (0.58) | PLAUPLGF2PLATPRSS1 | |
| Trifluoroacetic Acid SCHEMBL7337496 | 0.81 | F2 (0.55) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL7344312 | 0.81 | F2 (0.44) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL7336349 | 0.81 | F2 (0.56) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL7336352 | 0.81 | F2 (0.56) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL7337522 | 0.76 | PLAU (0.61) | PLAUPLGF2PLATPRSS1 | |
| Trifluoroacetic Acid SCHEMBL7402075 | 0.76 | F2 (0.53) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL7340950 | 0.73 | PLAU (1.00) | PLAUPLGF2PLATPRSS1 | |
| Trifluoroacetic Acid SCHEMBL7856136 | 0.70 | PLAU (0.86) | PLAUPLGF2PLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |