Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 18/20 | 0.86 |
| ▸ | PLG | P00747 | 12/20 | 0.86 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.86 |
| ▸ | F2 | P00734 | 10/20 | 0.86 |
| ▸ | PLAT | P00750 | 10/20 | 0.86 |
| ▸ | KLKB1 | P03952 | 9/20 | 0.86 |
| ▸ | KLK1 | P06870 | 3/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | PDE1A | P54750 | 1/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340950 | 0.93 | PLAU (1.00) | PLAUPLGPRSS1F2PLAT | |
| Trifluoroacetic Acid SCHEMBL7358911 | 0.84 | PLAU (0.62) | PLAUPLGPRSS1F2PLAT | |
| Trifluoroacetic Acid SCHEMBL7854751 | 0.84 | PLAU (0.87) | PLAUPLGPRSS1F2PLAT | |
| SCHEMBL7856137 | 0.83 | PLAU (0.67) | PLAUPLGPRSS1F2PLAT | |
| Trifluoroacetic Acid SCHEMBL7853915 | 0.81 | PLAU (0.86) | PLAUPLGPRSS1F2PLAT | |
| Trifluoroacetic Acid SCHEMBL7344307 | 0.80 | PLAU (0.56) | PLAUPLGPRSS1F2PLAT | |
| Trifluoroacetic Acid SCHEMBL7344364 | 0.79 | PLAU (0.65) | PLAUPLGPRSS1F2PLAT | |
| Trifluoroacetic Acid SCHEMBL7337496 | 0.79 | F2 (0.55) | PLAUPLGPRSS1F2PLAT | |
| Trifluoroacetic Acid SCHEMBL7853602 | 0.78 | PLAU (0.70) | PLAUPLGPRSS1F2PLAT | |
| Trifluoroacetic Acid SCHEMBL7402075 | 0.78 | F2 (0.53) | PLAUPLGPRSS1F2PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010049374-A1 | Urokinase inhibitors | STEELE ANDREW W (US) | 2001-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010049374-A1 | Urokinase inhibitors | SERPINE1, PLAU, SERPINB1 | PLAU 2/4885PLG 10/4885PRSS1 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.