Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.53 |
| ▸ | PLAU | P00749 | 6/20 | 0.53 |
| ▸ | PLG | P00747 | 5/20 | 0.53 |
| ▸ | PLAT | P00750 | 5/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.53 |
| ▸ | F3 | P13726 | 8/20 | 0.42 |
| ▸ | KLK1 | P06870 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7337496 | 0.95 | F2 (0.55) | F2PLAUPLGPLATPRSS1 | |
| SCHEMBL7336352 | 0.92 | F2 (0.56) | F2PLAUPLGPLATPRSS1 | |
| SCHEMBL7336349 | 0.92 | F2 (0.56) | F2PLAUPLGPLATPRSS1 | |
| SCHEMBL7336369 | 0.86 | PLAU (0.58) | F2PLAUPLGPLATPRSS1 | |
| Trifluoroacetic Acid SCHEMBL7344307 | 0.84 | PLAU (0.56) | F2PLAUPLGPLATPRSS1 | |
| SCHEMBL7402078 | 0.82 | F2 (0.40) | F2PLAUPLGPLATPRSS1 | |
| SCHEMBL7337500 | 0.79 | F2 (0.43) | F2PLAUPLGPLATPRSS1 | |
| Trifluoroacetic Acid SCHEMBL7856136 | 0.78 | PLAU (0.86) | F2PLAUPLGPLATPRSS1 | |
| SCHEMBL7342961 | 0.76 | PLAU (0.58) | F2PLAUPLGPLATPRSS1 | |
| Trifluoroacetic Acid SCHEMBL3897211 | 0.71 | F10 (0.70) | F2PLAUPLGPLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |