Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334640 | 0.93 | MAPT (0.43) | ALDH1A1KMT2AMEN1RECQLNPSR1 | |
| SCHEMBL7337787 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1HIF1ANPSR1 | |
| SCHEMBL7335754 | 0.89 | SIGMAR1 (0.40) | RECQLNPSR1MAPTKDM4EADRA1A | |
| SCHEMBL7343470 | 0.86 | MAPT (0.50) | ALDH1A1KMT2AMEN1RECQLNPSR1 | |
| SCHEMBL7345686 | 0.86 | RECQL (0.46) | ALDH1A1KMT2AMEN1RECQLNPSR1 | |
| SCHEMBL7347816 | 0.85 | TP53 (0.38) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL7780810 | 0.84 | TP53 (0.42) | KMT2AMEN1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL7346826 | 0.84 | HDAC3 (0.37) | ALDH1A1MAPTSMN1; SMN2KDM4EHTR1A | |
| SCHEMBL7338566 | 0.83 | HDAC3 (0.37) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL7342178 | 0.83 | KMT2A (0.39) | ALDH1A1KMT2AMEN1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |