Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339968 | 0.94 | ACHE (0.39) | BCHEACHEBACE1KDM4EALDH1A1 | |
| SCHEMBL7338668 | 0.89 | BCHE (0.38) | BCHEACHEBACE1KDM4EALDH1A1 | |
| SCHEMBL7026619 | 0.79 | CMA1 (0.46) | KDM4EALDH1A1MAPTSIGMAR1CMA1 | |
| SCHEMBL10126281 | 0.77 | ACHE (0.54) | BCHEACHEBACE1ALDH1A1MAPK1 | |
| SCHEMBL7376968 | 0.76 | MC4R (0.55) | BCHEACHEBACE1SIGMAR1GAA | |
| SCHEMBL7345749 | 0.76 | CMA1 (0.43) | KDM4EALDH1A1MAPTSIGMAR1CMA1 | |
| SCHEMBL7374665 | 0.75 | MAPT (0.46) | BCHEACHEBACE1MAPTHTT | |
| SCHEMBL7682041 | 0.72 | FUCA1 (0.49) | BCHEACHEBACE1KDM4EALDH1A1 | |
| SCHEMBL10067586 | 0.72 | FUCA1 (0.49) | BCHEACHEBACE1KDM4EALDH1A1 | |
| SCHEMBL1011768 | 0.72 | FUCA1 (0.49) | BCHEACHEBACE1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358599-A | Synthesis of 4-amino-1,2-hydrocarbyl pyrazolidines via 4-nitro analogs | A. H. ROBINS COMPANY, INC. (US) | 1982-11-09 | — | — | US | disclosed |
| US-4309552-A | Synthesis of 4-nitro-1,2-hydrocarbyl pyrazolidines and process for preparation thereof | A. H. ROBINS COMPANY, INC. (US) | 1982-01-05 | — | — | US | disclosed |