Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CBX7 | O95931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344872 | 0.82 | MCL1 (0.49) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6838793 | 0.82 | MCL1 (0.66) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3315538 | 0.82 | POLB (0.52) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL12217574 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7447346 | 0.81 | GAA (0.56) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8323913 | 0.80 | GAA (0.55) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30876366 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19317367 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL17935310 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8320409 | 0.78 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932582-A | Fibrinogen receptor antagonist prodrugs | MERCK & CO., INC. (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0912513-A1 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000401-A1 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |