Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | F12 | P00748 | 11/20 | 0.61 |
| ▸ | F2 | P00734 | 3/20 | 0.56 |
| ▸ | PLG | P00747 | 3/20 | 0.56 |
| ▸ | F10 | P00742 | 2/20 | 0.56 |
| ▸ | KLK1 | P06870 | 2/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.56 |
| ▸ | MLNR | O43193 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | C1R | P00736 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348303 | 0.94 | FTO (0.62) | MEN1KMT2ANPC1CASP3SENP8 | |
| SCHEMBL10889487 | 0.88 | KMT2A (0.56) | MEN1KMT2ANPC1CASP3SENP8 | |
| Hydrochloric Acid SCHEMBL11144929 | 0.86 | KMT2A (0.55) | MEN1KMT2ANPC1CASP3SENP8 | |
| SCHEMBL7337750 | 0.82 | F12 (0.71) | MEN1KMT2AF12F2PLG | |
| SCHEMBL7341905 | 0.81 | F12 (0.57) | F12F2PLGF10KLK1 | |
| SCHEMBL31380450 | 0.80 | F12 (0.76) | MEN1KMT2AF12F2PLG | |
| SCHEMBL31499303 | 0.80 | KMT2A (0.67) | MEN1KMT2ANPC1CASP3SENP8 | |
| SCHEMBL7347475 | 0.79 | F12 (0.60) | F12F2PLGF10KLK1 | |
| SCHEMBL7342919 | 0.79 | KMT2A (0.64) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL10698009 | 0.79 | FTO (0.59) | F12F2PLGF10KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048433-B1 | NOVEL AMIDINE COMPOUNDS, PROCESS FOR PRODUCING SAME AND ANTI-COMPLEMENT AGENT COMPRISING THEM | TORII & CO., LTD. (JP) | 1986-05-28 | — | — | EP | disclosed |
| US-4532255-A | Amidine compounds and anticomplement agent comprising same | TORII & CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |
| US-4454338-A | 6-AMIDINO-2-NATHTHYL-4-GUANIDINOBENZOATE | TORII & CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0048433-A2 | Novel amidine compounds, process for producing same and anti-complement agent comprising them | TORII & CO., LTD. (JP) | 1982-03-31 | — | — | EP | disclosed |