Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.48 |
| ▸ | TMPRSS15 | P98073 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11144929 | 0.98 | KMT2A (0.55) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL7743635 | 0.88 | F2 (0.48) | KMT2AMEN1MAPTLMNAPRSS1 | |
| SCHEMBL7343416 | 0.88 | MEN1 (0.62) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL10946105 | 0.87 | F2 (0.47) | KMT2AMEN1MAPTLMNAPRSS1 | |
| Hydrochloric Acid SCHEMBL10942391 | 0.86 | F2 (0.46) | KMT2AMEN1MAPTLMNAPRSS1 | |
| SCHEMBL17020027 | 0.85 | KMT2A (0.56) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL10945116 | 0.83 | ALDH1A1 (0.57) | KMT2APRSS1TMPRSS15ALDH1A1PARP10 | |
| SCHEMBL10894177 | 0.82 | MAPT (0.62) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL7348303 | 0.82 | FTO (0.62) | KMT2AMEN1MAPTLMNANPC1 | |
| Hydrochloric Acid SCHEMBL11144871 | 0.81 | MAPT (0.60) | KMT2AMEN1MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604285-A | ANTICOAGULANT | BEECHAM GROUP P.L.C. (GB) | 1986-08-05 | — | — | US | disclosed |
| EP-0151593-A1 | ENZYME DERIVATIVES. | BEECHAM GROUP PLC (GB) | 1985-08-21 | — | — | EP | disclosed |
| WO-1985000521-A1 | ENZYME DERIVATIVES | BEECHAM GROUP P.L.C. (GB) | 1985-02-14 | — | — | WO | disclosed |