Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341117 | 0.80 | ITGB3 (0.39) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7347196 | 0.78 | HTT (0.37) | ITGB3ITGA2BSMN1; SMN2GPR139MEN1 | |
| SCHEMBL7341549 | 0.77 | — | — | |
| SCHEMBL7346229 | 0.76 | ITGB3 (0.36) | ITGB3ITGA2BSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7348597 | 0.75 | ITGB3 (0.38) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7346500 | 0.74 | ITGB3 (0.60) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7343459 | 0.74 | KCNK3 (0.40) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7339879 | 0.73 | ITGB3 (0.43) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6773153 | 0.73 | ITGB3 (0.55) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7343615 | 0.73 | SMN1; SMN2 (0.38) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |