Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347801 | 0.79 | MAPT (0.42) | LMNATP53MAPTPOLBHSD17B10 | |
| Oxomemazine SCHEMBL29378205 | 0.78 | LMNA (0.60) | RXFP1LMNATP53MAPTPOLB | |
| Oxomemazine SCHEMBL423634 | 0.78 | LMNA (0.60) | RXFP1LMNATP53MAPTPOLB | |
| Oxomemazine SCHEMBL4420096 | 0.77 | LMNA (0.58) | RXFP1LMNATP53MAPTPOLB | |
| SCHEMBL19742355 | 0.77 | RXFP1 (0.47) | RXFP1LMNATP53MAPTPOLB | |
| SCHEMBL141530 | 0.73 | CHRM2 (0.62) | LMNATP53MAPTSLC6A2CHRM2 | |
| SCHEMBL29754774 | 0.73 | CHRM2 (0.62) | LMNATP53MAPTSLC6A2CHRM2 | |
| SCHEMBL22882778 | 0.73 | CHRM2 (0.55) | LMNATP53MAPTSLC6A2CHRM2 | |
| Hydrochloric Acid SCHEMBL4225623 | 0.72 | SLC6A4 (0.60) | LMNATP53MAPTTHRBSLC6A2 | |
| Hydrochloric Acid SCHEMBL30722984 | 0.72 | CHRM2 (0.60) | LMNATP53MAPTSLC6A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833138-A | Phenothiazinealkaneamines for treatment of neurotoxic injury | WASHINGTON UNIVERSITY (US) | 1989-05-23 | — | — | US | disclosed |