Oxomemazine

Oxomemazine

SCHEMBL29378205

CC(CN(C)C)CN1c2ccccc2S(=O)(=O)c2ccccc21

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 8/20 0.60
CHRM2 P08172 3/20 0.60
HTR1A P08908 3/20 0.60
ADRA2A P08913 3/20 0.60
CHRM1 P11229 3/20 0.60
DRD1 P21728 3/20 0.60
TBXA2R P21731 3/20 0.60
ADRA1A P35348 3/20 0.60
OPRM1 P35372 3/20 0.60
DRD3 P35462 3/20 0.60
KCNH2 Q12809 3/20 0.60
CYP3A4 P08684 3/20 0.60
CYP2D6 P10635 3/20 0.60
SLC6A2 P23975 2/20 0.60
SLC6A4 P31645 2/20 0.60
SLC6A3 Q01959 2/20 0.60
SLC22A1 O15245 1/20 0.60
CACNA1B Q00975 1/20 0.60
TSHR P16473 1/20 0.60
NFKB1 P19838 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxomemazine SCHEMBL423634 1.00 LMNA (0.60) LMNACHRM2HTR1AADRA2ACHRM1
Oxomemazine SCHEMBL4420096 0.98 LMNA (0.58) LMNACHRM2HTR1AADRA2ACHRM1
SCHEMBL22882778 0.78 CHRM2 (0.55) LMNACHRM2HTR1AADRA2ACHRM1
SCHEMBL7344181 0.78 RXFP1 (0.42) LMNACHRM2HTR1AADRA2ACHRM1
Oxomemazine SCHEMBL28086314 0.76 CYP2D6 (0.60) LMNACHRM2HTR1AADRA2ACHRM1
Trimipramine SCHEMBL117756 0.75 SLC6A4 (1.00) LMNACHRM2HTR1AADRA2ACHRM1
Trimipramine SCHEMBL5494378 0.75 SLC6A4 (1.00) LMNACHRM2HTR1AADRA2ACHRM1
Methylpromazine SCHEMBL18993 0.75 CHRM2 (1.00) LMNACHRM2HTR1AADRA2ACHRM1
Trimipramine SCHEMBL35144 0.75 SLC6A4 (1.00) LMNACHRM2HTR1AADRA2ACHRM1
SCHEMBL12265313 0.75 CYP2D6 (0.63) LMNACHRM2HTR1AADRA2ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119652760-A Intelligent arrangement method for service function chain of user experience perception 中国人民解放军国防科技大学 2025-03-18 CN claimed
US-20260015671-A1 METHOD FOR DETECTING LUNG CANCER GENOMICTREE INC (KR) 2026-01-15 US disclosed
EP-4647071-A1 MITOCHONDRIAL COMPLEX I MODULATOR FOR USE IN THE TREATMENT OF ARTHRITIS Istesso Therapeutics Limited (GB) 2025-11-12 EP disclosed
CN-119652760-A Intelligent arrangement method for service function chain of user experience perception 中国人民解放军国防科技大学 2025-03-18 CN disclosed
WO-2024233957-A2 COMPOSITIONS AND METHODS TO PREVENT, INHIBIT OR TREAT NEURODEGENERATIVE DISEASES THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-11-14 WO disclosed
EP-4431090-A1 SOLFONAMIDES ACTING AS MITOCHONDRIAL COMPLEX I MODULATOR COMPOUNDS Istesso 1 Limited (GB) 2024-09-18 EP disclosed
EP-4164666-A2 COMPOSITIONS AND METHODS FOR TREATING DISEASES AND DISORDERS USING HARRYFLINTIA ACETISPORA Evelo Biosciences, Inc. (US) 2023-04-19 EP disclosed
WO-2023034232-A1 A SMALL MOLECULE THERAPEUTIC FOR FRIEDREICH'S ATAXIA AND TAUOPATHY THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-03-09 WO disclosed
EP-3990434-A1 COMPOUNDS HAVING ANTIMALARIAL ACTIVITY Nanyang Technological University (SG) 2022-05-04 EP disclosed
WO-2022031859-A2 METHYLMALONIC ACID AND METABOLISM THEREOF IS A CANCER BIOMARKER AND TARGET CORNELL UNIVERSITY (US) 2022-02-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015671-A1 METHOD FOR DETECTING LUNG CANCER DSC1, DSG1, TET1 LMNA 4323/4885CHRM2 598/4885HTR1A 3502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.