Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 17/20 | 0.69 |
| ▸ | MMP1 | P03956 | 4/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362350 | 0.95 | MMP3 (0.69) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7340475 | 0.85 | MMP3 (0.65) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL6961405 | 0.82 | MMP3 (1.00) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7342416 | 0.81 | MMP3 (0.66) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7336654 | 0.81 | MMP3 (0.65) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7339940 | 0.80 | MMP3 (0.61) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL6951569 | 0.79 | MMP3 (1.00) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7339321 | 0.79 | MMP3 (0.66) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7334810 | 0.78 | MMP3 (0.67) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7345078 | 0.78 | MMP3 (0.65) | MMP3MMP1MMP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847148-A | Thiadiazole derivatives useful for the treatment of diseases related to connective tissue degradation | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | disclosed |