Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | CTSK | P43235 | 4/20 | 0.56 |
| ▸ | IL1RN | P18510 | 1/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344529 | 1.00 | CTSS (0.56) | CTSSCTSLCTSKIL1RNERAP2 | |
| SCHEMBL7339988 | 0.94 | CTSK (0.58) | CTSSCTSLCTSKIL1RNERAP2 | |
| SCHEMBL7345719 | 0.94 | CTSK (0.58) | CTSSCTSLCTSKIL1RNERAP2 | |
| SCHEMBL7335815 | 0.93 | CTSK (0.57) | CTSSCTSLCTSKIL1RNERAP2 | |
| SCHEMBL7335812 | 0.93 | CTSK (0.57) | CTSSCTSLCTSKIL1RNERAP2 | |
| SCHEMBL7339972 | 0.92 | CTSS (0.57) | CTSSCTSLCTSKIL1RNERAP2 | |
| SCHEMBL7338757 | 0.92 | GAA (0.61) | CTSSCTSLCTSKIL1RNERAP2 | |
| SCHEMBL7339964 | 0.92 | CTSS (0.57) | CTSSCTSLCTSKIL1RNERAP2 | |
| SCHEMBL7341802 | 0.92 | CTSK (0.62) | CTSSCTSLCTSKIL1RNERAP2 | |
| SCHEMBL7341796 | 0.92 | CTSK (0.62) | CTSSCTSLCTSKIL1RNERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |