Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CTSL | P07711 | 5/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344682 | 1.00 | CTSK (0.48) | CTSKCTSLCTSSPSEN1PSEN2 | |
| SCHEMBL7335989 | 0.84 | CTSK (0.47) | CTSKCTSLPSEN1PSEN2APH1B | |
| SCHEMBL7335996 | 0.84 | CTSK (0.47) | CTSKCTSLPSEN1PSEN2APH1B | |
| SCHEMBL7370417 | 0.82 | CTSK (0.45) | CTSKCTSLCTSSPSEN1PSEN2 | |
| SCHEMBL7370421 | 0.82 | CTSK (0.45) | CTSKCTSLCTSSPSEN1PSEN2 | |
| SCHEMBL9227916 | 0.82 | CTSK (0.45) | CTSKCTSLCTSSPSEN1PSEN2 | |
| SCHEMBL7343508 | 0.82 | CTSK (0.45) | CTSKCTSLCTSSPSEN1PSEN2 | |
| SCHEMBL7344318 | 0.75 | CTSK (0.43) | CTSKCTSLCTSSPSEN1PSEN2 | |
| SCHEMBL7344306 | 0.75 | CTSK (0.43) | CTSKCTSLCTSSPSEN1PSEN2 | |
| SCHEMBL8823957 | 0.74 | CTSK (0.55) | CTSKCTSLCTSSPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416117-A | Protease inhibitor | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0520427-B1 | Cyclopropenone derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328909-A | Protease inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0520427-A1 | Cyclopropenone derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-30 | — | — | EP | disclosed |