Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.42 |
| ▸ | CTSL | P07711 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823956 | 0.99 | CTSK (0.53) | CTSKCTSSCAPN1CTSLSMN1; SMN2 | |
| SCHEMBL7340018 | 0.81 | CTSK (0.56) | CTSKCTSSSMN1; SMN2 | |
| SCHEMBL7340009 | 0.81 | CTSK (0.56) | CTSKCTSSSMN1; SMN2 | |
| SCHEMBL4144410 | 0.80 | CTSK (0.55) | CTSKCTSSSMN1; SMN2 | |
| SCHEMBL4136042 | 0.78 | CTSK (0.54) | CTSKCTSSSMN1; SMN2 | |
| SCHEMBL8807983 | 0.74 | CTSK (0.56) | CTSKCAPN1 | |
| SCHEMBL8807975 | 0.74 | CTSK (0.56) | CTSKCAPN1 | |
| SCHEMBL11977974 | 0.74 | CTSK (0.47) | CTSKCTSL | |
| SCHEMBL7344682 | 0.74 | CTSK (0.48) | CTSKCTSSCTSLPSEN1PSEN2 | |
| SCHEMBL7344674 | 0.74 | CTSK (0.48) | CTSKCTSSCTSLPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049668-A1 | INHIBITIORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | claimed |