Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 6/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.45 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 4/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339127 | 0.93 | AVPR2 (0.44) | AVPR2AVPR1AAVPR1BRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7342655 | 0.92 | AVPR2 (0.43) | AVPR2AVPR1AAVPR1BRAB9ASMN1; SMN2 | |
| SCHEMBL7340679 | 0.91 | AVPR2 (0.49) | AVPR2AVPR1AAVPR1BRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7337716 | 0.91 | AVPR2 (0.44) | AVPR2AVPR1AAVPR1BRAB9ASMN1; SMN2 | |
| SCHEMBL7374171 | 0.91 | AVPR2 (0.56) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7338793 | 0.91 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BRAB9ASMN1; SMN2 | |
| SCHEMBL7341258 | 0.90 | AVPR2 (0.45) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL7743965 | 0.89 | AVPR2 (0.52) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7337768 | 0.89 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BRAB9ASMN1; SMN2 | |
| SCHEMBL8008232 | 0.88 | ALDH1A1 (0.47) | AVPR2AVPR1AAVPR1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |