Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.45 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339504 | 0.93 | AVPR2 (0.43) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7780668 | 0.93 | ALDH1A1 (0.44) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7780700 | 0.93 | AVPR2 (0.48) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7778671 | 0.92 | ALDH1A1 (0.44) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7335554 | 0.91 | ALDH1A1 (0.45) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL8611049 | 0.91 | ALDH1A1 (0.44) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7338937 | 0.90 | KMT2A (0.44) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| Hydrochloric Acid SCHEMBL7337716 | 0.89 | AVPR2 (0.44) | AVPR2AVPR1AAVPR1BBRPF1 | |
| SCHEMBL7374171 | 0.89 | AVPR2 (0.56) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7743965 | 0.89 | AVPR2 (0.52) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |