SCHEMBL7344827

SCHEMBL7344827

CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@@H](CC1CC1)NC(=O)C(CSC(C)(C)C)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7348709 0.86 REN (0.78) REN
SCHEMBL5709668 0.86 REN (0.61) REN
SCHEMBL5709674 0.83 REN (0.62) REN
SCHEMBL5709605 0.80 REN (0.49) REN
SCHEMBL7417645 0.80 REN (0.49) REN
SCHEMBL5709621 0.80 REN (0.60) REN
SCHEMBL5709629 0.77 REN (0.60) REN
SCHEMBL7327623 0.77 REN (0.63) REN
SCHEMBL7337682 0.76 REN (0.61) REN
SCHEMBL7337568 0.76 REN (0.61) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5317039-A Renin inhibitors with peptides G. D. SEARLE & CO. (US) 1994-05-31 US claimed