SCHEMBL7327623

SCHEMBL7327623

CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC1CC1)[C@H](O)C[C@H](O)Cc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7327628 0.90 REN (0.51) REN
SCHEMBL5709600 0.81 REN (0.66) REN
SCHEMBL7280154 0.79 REN (0.62) REN
SCHEMBL7280042 0.79 REN (0.62) REN
SCHEMBL7344827 0.77 REN (0.64) REN
SCHEMBL7390038 0.76 REN (0.60) REN
SCHEMBL7348709 0.76 REN (0.78) REN
SCHEMBL7337682 0.76 REN (0.61) REN
SCHEMBL7337568 0.76 REN (0.61) REN
SCHEMBL9249864 0.75 REN (0.62) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5354767-A Renin inhibiting polyhydroxy-monoamides BIO-MEGA, INC. (CA) 1994-10-11 US disclosed