Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 7/20 | 0.41 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7344968 | 0.90 | ITGB3 (0.51) | PLAUCTSSCTSKCTSBASIC3 | |
| SCHEMBL7339140 | 0.87 | PLAU (0.51) | PLAUCTSSCTSKCTSBASIC3 | |
| Trifluoroacetic Acid SCHEMBL7335751 | 0.72 | PLAU (0.80) | PLAUASIC3 | |
| SCHEMBL7394806 | 0.71 | ACE (0.58) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL7394803 | 0.71 | ACE (0.58) | CTSSCTSKCTSBITGB3ITGA2B | |
| Iodide SCHEMBL7301004 | 0.71 | ACE (0.57) | CTSSCTSKCTSBITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL5671540 | 0.71 | ACE (0.57) | CTSSCTSKCTSBITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7353483 | 0.70 | ASIC3 (0.64) | PLAUASIC3 | |
| SCHEMBL13651743 | 0.70 | KLK5 (0.54) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL28472380 | 0.70 | KLK5 (0.60) | CTSSCTSKCTSBITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |