Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850625 | 0.81 | HSD17B10 (0.49) | HSD17B10HPGDUSP2ALDH1A1HTR2A | |
| SCHEMBL7345457 | 0.78 | HPGD (0.47) | HSD17B10HPGDUSP2ALDH1A1HTR2A | |
| SCHEMBL22868261 | 0.78 | HTR2A (0.47) | HSD17B10HPGDUSP2ALDH1A1HTR2A | |
| SCHEMBL1752256 | 0.77 | HPGD (0.46) | HSD17B10HPGDUSP2ALDH1A1HTR2A | |
| SCHEMBL30040327 | 0.77 | HSD17B10 (0.46) | HSD17B10HPGDUSP2ALDH1A1HTR2A | |
| SCHEMBL9431800 | 0.77 | MCL1 (0.49) | HSD17B10HPGDUSP2ALDH1A1HTR2A | |
| SCHEMBL9635353 | 0.76 | DRD2 (0.59) | HSD17B10HPGDUSP2ALDH1A1HTR2A | |
| Hydrochloric Acid SCHEMBL5906542 | 0.76 | HPGD (0.45) | HSD17B10HPGDUSP2ALDH1A1HTR2A | |
| SCHEMBL9431245 | 0.73 | MCL1 (0.45) | HSD17B10HPGDUSP2ALDH1A1HTR2A | |
| SCHEMBL31276319 | 0.69 | CRBN (0.54) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990015058-A1 | HETEROCYCLIC AMINES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY | THE UPJOHN COMPANY (US) | 1990-12-13 | — | — | WO | disclosed |