Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 6/20 | 0.65 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | DHODH | Q02127 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.52 |
| ▸ | RARA | P10276 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | RARG | P13631 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23440273 | 0.84 | ALDH1A1 (0.58) | CDC7DBF4ALDH1A1HPGDDHODH | |
| SCHEMBL4503056 | 0.84 | CDC7 (0.88) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL953385 | 0.79 | CDC7 (1.00) | CDC7DBF4ALDH1A1HSD17B10TRPM8 | |
| SCHEMBL16039074 | 0.78 | CDC7 (0.76) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL8823153 | 0.78 | ALDH1A1 (0.75) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL16037743 | 0.77 | LMNA (0.74) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL1919084 | 0.76 | ALDH1A1 (0.74) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL6502690 | 0.76 | ALDH1A1 (0.73) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL952275 | 0.76 | CDC7 (0.73) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL330552 | 0.75 | ALDH1A1 (1.00) | CDC7DBF4ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342851-A | Useful in methods of treating reperfusion thrombosis injury | MCNEIL-PPC, INC. (US) | 1994-08-30 | — | — | US | disclosed |