Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 3/20 | 0.52 |
| ▸ | MMP13 | P45452 | 3/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 13/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351650 | 0.94 | MMP12 (0.54) | MMP12MMP13TBXAS1MMP7GLA | |
| SCHEMBL7351035 | 0.91 | MMP13 (0.60) | MMP12MMP13MMP7 | |
| SCHEMBL7352707 | 0.88 | MMP13 (0.59) | MMP12MMP13MMP7 | |
| SCHEMBL7346019 | 0.87 | MMP12 (0.47) | MMP12MMP13TBXAS1MMP7GLA | |
| SCHEMBL7349914 | 0.87 | MMP13 (0.58) | MMP12MMP13MMP7 | |
| SCHEMBL4425589 | 0.84 | MMP12 (0.62) | MMP12MMP13MMP7 | |
| SCHEMBL4425599 | 0.84 | MMP12 (0.62) | MMP12MMP13MMP7 | |
| SCHEMBL7347760 | 0.84 | MMP12 (0.58) | MMP12MMP13MMP7 | |
| SCHEMBL7351949 | 0.84 | MMP13 (0.55) | MMP12MMP13MMP7 | |
| SCHEMBL7343982 | 0.82 | MMP12 (0.40) | MMP12MMP13TBXAS1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929542-A1 | COMPOUNDS FOR AND A METHOD OF INHIBITING MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1999-07-21 | — | — | EP | claimed |
| WO-1998009957-A1 | COMPOUNDS FOR AND A METHOD OF INHIBITING MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1998-03-12 | — | — | WO | claimed |
| EP-0929542-A1 | COMPOUNDS FOR AND A METHOD OF INHIBITING MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998009957-A1 | COMPOUNDS FOR AND A METHOD OF INHIBITING MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1998-03-12 | — | — | WO | disclosed |