Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7342139 | 0.95 | ITGB3 (0.40) | ITGB3ITGA2BALOX15HRH3WNT1 | |
| SCHEMBL7345353 | 0.86 | ITGB3 (0.47) | ITGB3ITGA2BALOX15HRH3GPR119 | |
| SCHEMBL7344621 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2BALOX15HRH3KMT2A | |
| SCHEMBL7299587 | 0.85 | HRH3 (0.36) | HRH3GPR119KMT2AMEN1EGFR | |
| SCHEMBL7346600 | 0.83 | MEN1 (0.37) | ITGB3ITGA2BALOX15HRH3WNT1 | |
| SCHEMBL7344852 | 0.81 | ITGB3 (0.45) | ITGB3ITGA2BALOX15HRH3WNT1 | |
| SCHEMBL7345105 | 0.81 | ITGB3 (0.52) | ITGB3ITGA2BALOX15HRH3WNT1 | |
| SCHEMBL9373233 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2BALOX15HRH3GPR119 | |
| Trifluoroacetic Acid SCHEMBL7344936 | 0.78 | PPARG (0.36) | ITGB3ITGA2BALOX15HRH3WNT1 | |
| SCHEMBL7338384 | 0.78 | ITGB3 (0.54) | ITGB3ITGA2BALOX15HRH3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | claimed |
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |