Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346600 | 0.95 | MEN1 (0.37) | HRH3HPGDSMN1; SMN2KDM4EABL1 | |
| Trifluoroacetic Acid SCHEMBL7339489 | 0.89 | ITGB3 (0.45) | HRH3DPP4DPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL7339244 | 0.85 | KDM4E (0.40) | SMN1; SMN2KDM4EITGB3ITGA2BMEN1 | |
| Trifluoroacetic Acid SCHEMBL7342139 | 0.84 | ITGB3 (0.40) | PPARDPPARAHRH3SMN1; SMN2KDM4E | |
| Trifluoroacetic Acid SCHEMBL7339521 | 0.84 | KDM4E (0.39) | SMN1; SMN2KDM4EITGB3ITGA2BMEN1 | |
| Trifluoroacetic Acid SCHEMBL7344932 | 0.84 | ITGB3 (0.49) | PPARGPPARDPPARAHRH3KDM4E | |
| SCHEMBL7345723 | 0.83 | ITGB3 (0.49) | HRH3KDM4EABL1LMNAITGB3 | |
| Trifluoroacetic Acid SCHEMBL7334117 | 0.83 | MEN1 (0.36) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL7345353 | 0.82 | ITGB3 (0.47) | HRH3HPGDSMN1; SMN2KDM4EITGB3 | |
| SCHEMBL7343064 | 0.79 | GAA (0.39) | SMN1; SMN2KDM4EITGB3ITGA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |