Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 7/20 | 0.63 |
| ▸ | TPH2 | Q8IWU9 | 2/20 | 0.60 |
| ▸ | MME | P08473 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345132 | 1.00 | TPH1 (0.63) | TPH1TPH2MMEMAOBGRIA2 | |
| Hydrochloric Acid SCHEMBL16816868 | 0.99 | TPH1 (0.62) | TPH1TPH2MMEMAOBGRIA2 | |
| Hydrochloric Acid SCHEMBL16816865 | 0.99 | TPH1 (0.62) | TPH1TPH2MMEMAOBGRIA2 | |
| SCHEMBL31369825 | 0.90 | GRIA2 (0.66) | TPH1GRIA2SLC7A5ALPIPKM | |
| SCHEMBL1676859 | 0.88 | MME (0.56) | TPH1TPH2MMEMAOBHSD17B2 | |
| SCHEMBL5069330 | 0.88 | MME (0.56) | TPH1TPH2MMEMAOBHSD17B2 | |
| Hydrochloric Acid SCHEMBL1676855 | 0.87 | MAOB (0.56) | TPH1TPH2MMEMAOBHSD17B2 | |
| Hydrochloric Acid SCHEMBL1676860 | 0.87 | MAOB (0.56) | TPH1TPH2MMEMAOBHSD17B2 | |
| SCHEMBL31688639 | 0.86 | GRIA2 (0.64) | TPH1GRIA2SLC7A5ALPIPKM | |
| SCHEMBL17892350 | 0.86 | PTAFR (0.54) | TPH1TPH2MMEMAOBSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042188-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING HCV INFECTION | Tokyo Metropolitan Organization for Medical Research (JP) | 2009-04-01 | — | — | EP | disclosed |
| EP-1908846-A1 | METHOD OF PRODUCING COMPOUND HAVING ANTI-HCV ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-04-09 | — | — | EP | disclosed |
| CN-1301964-C | Inhibitors of alpha 4-mediated cell adhesion | TANABE SEIYAKU CO (JP) | 2007-02-28 | — | — | CN | disclosed |
| CN-1288457-A | Inhibitors of & alpha, 4 mediated cell adhesion | TANABE SEIYAKU CO (JP) | 2001-03-21 | — | — | CN | disclosed |
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |