Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | TPH1 | P17752 | 4/20 | 0.52 |
| ▸ | TPH2 | Q8IWU9 | 2/20 | 0.49 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1676859 | 1.00 | MME (0.56) | MMEMAOBTPH1TPH2SLC13A5 | |
| Hydrochloric Acid SCHEMBL1676855 | 0.99 | MAOB (0.56) | MMEMAOBTPH1TPH2SLC13A5 | |
| Hydrochloric Acid SCHEMBL1676860 | 0.99 | MAOB (0.56) | MMEMAOBTPH1TPH2SLC13A5 | |
| SCHEMBL7345126 | 0.88 | TPH1 (0.63) | MMEMAOBTPH1TPH2SLC13A5 | |
| SCHEMBL7345132 | 0.88 | TPH1 (0.63) | MMEMAOBTPH1TPH2SLC13A5 | |
| SCHEMBL2074406 | 0.88 | MAOB (0.50) | MMEMAOBTPH1TPH2SLC13A5 | |
| Hydrochloric Acid SCHEMBL16816868 | 0.87 | TPH1 (0.62) | MMEMAOBTPH1TPH2SLC13A5 | |
| Hydrochloric Acid SCHEMBL16816865 | 0.87 | TPH1 (0.62) | MMEMAOBTPH1TPH2SLC13A5 | |
| Hydrochloric Acid SCHEMBL2074402 | 0.87 | MAOB (0.51) | MMEMAOBTPH1TPH2SLC13A5 | |
| SCHEMBL539241 | 0.86 | LDHA (0.54) | MAOBTPH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908846-A1 | METHOD OF PRODUCING COMPOUND HAVING ANTI-HCV ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-04-09 | — | — | EP | disclosed |