Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PPID | Q08752 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | PPIB | P23284 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | PPIG | Q13427 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343265 | 0.89 | MAPT (0.54) | MAPTPOLBLMNASMN1; SMN2CYP4Z1 | |
| SCHEMBL7346083 | 0.89 | MAPT (0.54) | MAPTPOLBLMNASMN1; SMN2CYP4Z1 | |
| SCHEMBL11458148 | 0.88 | MAPT (0.67) | MAPTPOLBLMNASMN1; SMN2CYP4Z1 | |
| SCHEMBL23310021 | 0.88 | POLB (0.66) | MAPTPOLBLMNASMN1; SMN2KDM4E | |
| SCHEMBL9742443 | 0.88 | POLB (0.61) | MAPTPOLBLMNASMN1; SMN2KDM4E | |
| SCHEMBL11802177 | 0.88 | MAPT (0.59) | MAPTPOLBLMNASMN1; SMN2CYP4Z1 | |
| SCHEMBL7339369 | 0.87 | ALDH1A1 (0.58) | MAPTPOLBLMNASMN1; SMN2CYP4Z1 | |
| Hydrochloric Acid SCHEMBL11798488 | 0.86 | MAPT (0.61) | MAPTPOLBLMNASMN1; SMN2CYP4Z1 | |
| SCHEMBL28088277 | 0.85 | POLB (0.58) | MAPTPOLBLMNASMN1; SMN2KDM4E | |
| SCHEMBL11473930 | 0.85 | MAPT (0.63) | MAPTPOLBLMNASMN1; SMN2CYP4Z1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622984-A | INHIBITORS OF PHOSPHOLIPASE, VARIOUS PROTEASES | ONO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-22 | — | — | US | disclosed |
| US-5614555-A | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0588655-A1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |