Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PPID | Q08752 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345267 | 0.87 | MAPT (0.65) | ALDH1A1MAPTPOLBPPIDGAA | |
| SCHEMBL62893 | 0.85 | POLB (0.60) | ALDH1A1MAPK1MAPTPOLBPPID | |
| SCHEMBL7336552 | 0.85 | PKM (0.67) | ALDH1A1L3MBTL1MAPTPKMGAA | |
| SCHEMBL62534 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL133175 | 0.84 | POLB (0.59) | ALDH1A1MAPK1MAPTPOLBPPID | |
| SCHEMBL15761774 | 0.83 | MAPT (0.72) | ALDH1A1L3MBTL1MAPTPPIDKLK7 | |
| Acetic Acid SCHEMBL28661029 | 0.82 | POLB (0.57) | ALDH1A1MAPK1MAPTPKMPOLB | |
| Hydrochloric Acid SCHEMBL27368126 | 0.82 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1MAPTPOLB | |
| Alcohol SCHEMBL28628021 | 0.82 | POLB (0.57) | ALDH1A1MAPK1MAPTPOLBPPID | |
| SCHEMBL11732203 | 0.81 | POLB (0.56) | ALDH1A1MAPK1MAPTPOLBPPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622984-A | INHIBITORS OF PHOSPHOLIPASE, VARIOUS PROTEASES | ONO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-22 | — | — | US | disclosed |
| US-5614555-A | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5432178-A | Substituted benzoic acid esters; use to prevent or treat inflammatory diseases, allergic diseases, disseminated intravascular coagulation, pancreatitis or multiple organ failure | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0588655-A1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |