Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 20/20 | 0.67 |
| ▸ | MMP3 | P08254 | 17/20 | 0.67 |
| ▸ | MMP13 | P45452 | 14/20 | 0.67 |
| ▸ | MMP7 | P09237 | 14/20 | 0.67 |
| ▸ | MMP9 | P14780 | 11/20 | 0.65 |
| ▸ | MMP2 | P08253 | 2/20 | 0.64 |
| ▸ | MMP8 | P22894 | 2/20 | 0.64 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339164 | 0.87 | MMP1 (0.51) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL6269273 | 0.86 | MMP3 (0.63) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL7349862 | 0.82 | MMP1 (0.91) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL7763139 | 0.81 | MMP1 (0.98) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL6981692 | 0.80 | MMP1 (1.00) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL7393667 | 0.80 | MMP1 (1.00) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL7413344 | 0.80 | MMP1 (1.00) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL7533064 | 0.78 | MMP1 (0.91) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL7533059 | 0.78 | MMP1 (0.91) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL6394072 | 0.78 | MMP1 (0.76) | MMP1MMP3MMP13MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923563-A1 | 1,4-HETEROCYCLIC METALLPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008825-A1 | 1,4-HETEROCYCLIC METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |