Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336265 | 0.93 | AVPR2 (0.42) | SMN1; SMN2GAALMNA | |
| SCHEMBL7339957 | 0.92 | AVPR2 (0.40) | SMN1; SMN2GAAKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7345642 | 0.92 | AVPR2 (0.42) | SMN1; SMN2GAALMNA | |
| SCHEMBL7778635 | 0.92 | AVPR2 (0.40) | SMN1; SMN2GAAKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7773784 | 0.92 | AVPR2 (0.42) | SMN1; SMN2GAALMNA | |
| SCHEMBL7773828 | 0.92 | AVPR2 (0.40) | SMN1; SMN2HPGDGAAKMT2AALDH1A1 | |
| SCHEMBL7345290 | 0.92 | BRPF1 (0.38) | SMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL7346737 | 0.92 | AVPR2 (0.39) | SMN1; SMN2GAAKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7345860 | 0.92 | AVPR2 (0.39) | SMN1; SMN2GAAKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7336802 | 0.92 | AVPR2 (0.39) | SMN1; SMN2HPGDGAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |