Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.40 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7346737 | 0.99 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BCCR8TP53 | |
| SCHEMBL7339957 | 0.95 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BCCR8TP53 | |
| SCHEMBL7773828 | 0.95 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BCCR8TP53 | |
| Hydrochloric Acid SCHEMBL7345860 | 0.94 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BCCR8TP53 | |
| Hydrochloric Acid SCHEMBL7336802 | 0.94 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BCCR8TP53 | |
| SCHEMBL7338630 | 0.94 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BCCR8TP53 | |
| Hydrochloric Acid SCHEMBL7780840 | 0.94 | AVPR2 (0.45) | AVPR2AVPR1AAVPR1BCCR8TP53 | |
| SCHEMBL7336265 | 0.93 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BCCR8TP53 | |
| SCHEMBL7345290 | 0.92 | BRPF1 (0.38) | AVPR2AVPR1AAVPR1BCCR8TP53 | |
| SCHEMBL7345334 | 0.92 | SMN1; SMN2 (0.42) | GAALMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |