Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338105 | 0.97 | AVPR2 (0.42) | METLMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL7342173 | 0.94 | AVPR2 (0.43) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7345955 | 0.94 | MEN1 (0.40) | METMAPTSMN1; SMN2AVPR2AVPR1A | |
| SCHEMBL7336940 | 0.94 | LMNA (0.41) | LMNAMAPTHTTSMN1; SMN2AVPR2 | |
| SCHEMBL7342320 | 0.93 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1B | |
| Hydrochloric Acid SCHEMBL7346689 | 0.93 | LMNA (0.41) | LMNAMAPTHTTSMN1; SMN2AVPR2 | |
| SCHEMBL7370102 | 0.92 | MEN1 (0.45) | MAPTSMN1; SMN2NAMPT | |
| SCHEMBL7342022 | 0.91 | LMNA (0.39) | LMNAMAPTHTTSMN1; SMN2AVPR2 | |
| SCHEMBL7336282 | 0.91 | AVPR2 (0.39) | LMNAMAPTHTTSMN1; SMN2AVPR2 | |
| Hydrochloric Acid SCHEMBL7778650 | 0.91 | LMNA (0.39) | LMNAMAPTHTTSMN1; SMN2AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |