Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338105 | 0.96 | AVPR2 (0.42) | MEN1KMT2AAVPR2AVPR1AAVPR1B | |
| SCHEMBL7345660 | 0.94 | MET (0.43) | AVPR2AVPR1AAVPR1BMETSMN1; SMN2 | |
| SCHEMBL7342173 | 0.93 | AVPR2 (0.43) | AVPR2AVPR1AAVPR1BBRD4 | |
| SCHEMBL7342320 | 0.92 | AVPR2 (0.41) | MEN1KMT2AAVPR2AVPR1AAVPR1B | |
| SCHEMBL7344389 | 0.91 | ALDH1A1 (0.42) | MEN1KMT2AHPGDALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7336491 | 0.91 | ALDH1A1 (0.42) | MEN1KMT2AHPGDALDH1A1CYP1A2 | |
| SCHEMBL7370102 | 0.90 | MEN1 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7349148 | 0.89 | MEN1 (0.44) | MEN1KMT2AHPGDALDH1A1CYP1A2 | |
| SCHEMBL7780638 | 0.88 | AVPR2 (0.44) | MEN1KMT2AAVPR2AVPR1AAVPR1B | |
| SCHEMBL7345366 | 0.87 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |