Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 9/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337503 | 0.99 | TACR2 (0.49) | TACR2ITGB3ITGA2BCTSSPPARG | |
| SCHEMBL7335392 | 0.95 | TACR2 (0.56) | TACR2ITGB3ITGA2BPLGPRSS1 | |
| SCHEMBL7344535 | 0.93 | TACR2 (0.60) | TACR2 | |
| SCHEMBL7337265 | 0.90 | TACR2 (0.56) | TACR2ITGB3ITGA2BPLGPRSS1 | |
| SCHEMBL7343369 | 0.89 | TACR2 (0.46) | TACR2PPARGPLGPRSS1PRSS2 | |
| SCHEMBL7341933 | 0.87 | PPARG (0.50) | TACR2CTSSPPARGPLGPRSS1 | |
| SCHEMBL7345736 | 0.87 | REN (0.51) | CTSSPPARGPLGPRSS1PRSS2 | |
| SCHEMBL7344329 | 0.86 | SLC2A1 (0.47) | TACR2PPARGPLGPRSS1PRSS2 | |
| SCHEMBL7345597 | 0.86 | TACR2 (0.49) | TACR2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7341957 | 0.86 | PLG (0.50) | TACR2PPARGPLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |