Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 6/20 | 0.43 |
| ▸ | YAP1 | P46937 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345870 | 0.86 | TACR2 (0.50) | PLGPRSS1PRSS2PRSS3TACR2 | |
| SCHEMBL7337503 | 0.86 | TACR2 (0.49) | PLGPRSS1PRSS2PRSS3TACR2 | |
| SCHEMBL7335392 | 0.85 | TACR2 (0.56) | PLGPRSS1PRSS2PRSS3TACR2 | |
| SCHEMBL7343369 | 0.84 | TACR2 (0.46) | PLGPRSS1PRSS2PRSS3TACR2 | |
| SCHEMBL7345597 | 0.83 | TACR2 (0.49) | PLGPRSS1PRSS2PRSS3TACR2 | |
| SCHEMBL7341933 | 0.83 | PPARG (0.50) | PLGPRSS1PRSS2PRSS3TACR2 | |
| SCHEMBL7345736 | 0.83 | REN (0.51) | PLGPRSS1PRSS2PRSS3PPARG | |
| SCHEMBL7344333 | 0.83 | SLC2A1 (0.50) | SLC2A1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7338801 | 0.83 | YAP1 (0.43) | CHRNB2CHRNA5CHRNA7CHRNA4YAP1 | |
| SCHEMBL7337265 | 0.83 | TACR2 (0.56) | PLGPRSS1PRSS2PRSS3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |