Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.55 |
| ▸ | TACR2 | P21452 | 9/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | IL1RN | P18510 | 1/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337508 | 0.99 | CTSS (0.55) | CTSSTACR2CTSKITGB3ITGA2B | |
| SCHEMBL7335394 | 0.95 | TACR2 (0.62) | CTSSTACR2ITGB3ITGA2B | |
| SCHEMBL7344537 | 0.93 | TACR2 (0.64) | TACR2 | |
| SCHEMBL7337268 | 0.89 | TACR2 (0.61) | TACR2ITGB3ITGA2B | |
| SCHEMBL7339423 | 0.89 | TACR2 (0.55) | TACR2ITGB3ITGA2BERAP2 | |
| SCHEMBL7408154 | 0.88 | CTSS (0.54) | CTSSTACR2CTSKITGB3ITGA2B | |
| SCHEMBL7337619 | 0.88 | CACNA1B (0.57) | CTSSTACR2CTSKCTSLPTPN1 | |
| SCHEMBL7340969 | 0.88 | CACNA1B (0.57) | CTSSTACR2CTSKCTSLPTPN1 | |
| SCHEMBL7344798 | 0.88 | TACR2 (0.53) | CTSSTACR2ITGB3ITGA2BPLG | |
| SCHEMBL7343374 | 0.88 | TACR2 (0.49) | CTSSTACR2CTSKIL1RNERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |