Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337048 | 0.89 | CACNA1B (0.48) | PSMB5CACNA1BACACB | |
| SCHEMBL7338606 | 0.83 | CACNA1B (0.42) | CACNA1BACACB | |
| SCHEMBL7346892 | 0.83 | CACNA1B (0.47) | PSMB5CACNA1BACACB | |
| SCHEMBL7338188 | 0.82 | KMT2A (0.44) | PSMB5CACNA1B | |
| SCHEMBL7346012 | 0.81 | FFAR1 (0.42) | FFAR1PTGESAKR1C3ACACB | |
| SCHEMBL7346468 | 0.79 | CACNA1B (0.40) | PSMB5CACNA1BACACB | |
| SCHEMBL7343134 | 0.79 | MMP1 (0.52) | PSMB5CACNA1B | |
| SCHEMBL7348068 | 0.79 | PSMB5 (0.51) | PSMB5CACNA1B | |
| SCHEMBL7338162 | 0.78 | MME (0.56) | CACNA1B | |
| SCHEMBL7347212 | 0.78 | FFAR1 (0.45) | FFAR1PSMB5CACNA1BACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |