Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 7/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8008651 | 0.99 | ADRA1D (0.35) | ADRA1DADRA1AADRA1BAVPR2AVPR1A | |
| SCHEMBL7342281 | 0.92 | AVPR2 (0.40) | ADRA1DADRA1AADRA1BAVPR2AVPR1A | |
| SCHEMBL7336963 | 0.92 | AVPR2 (0.40) | ADRA1DADRA1AADRA1BAVPR2AVPR1A | |
| SCHEMBL7778619 | 0.92 | AVPR2 (0.40) | ADRA1DADRA1AADRA1BAVPR2AVPR1A | |
| Hydrochloric Acid SCHEMBL7336806 | 0.92 | AVPR2 (0.39) | ADRA1DADRA1AADRA1BAVPR2AVPR1A | |
| Hydrochloric Acid SCHEMBL7778624 | 0.92 | AVPR2 (0.39) | ADRA1DADRA1AADRA1BAVPR2AVPR1A | |
| Hydrochloric Acid SCHEMBL7336828 | 0.92 | AVPR2 (0.39) | ADRA1DADRA1AADRA1BAVPR2AVPR1A | |
| Hydrochloric Acid SCHEMBL7335547 | 0.87 | MAP3K7 (0.35) | ADRA1DADRA1AADRA1BAVPR2AVPR1A | |
| SCHEMBL7342048 | 0.87 | LMNA (0.38) | MAP3K7TP53GAA | |
| SCHEMBL7337579 | 0.86 | AVPR2 (0.34) | ADRA1DADRA1AADRA1BAVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |