Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346150 | 0.90 | CYP2D6 (0.35) | SLC6A4HRH3DRD2HTR1AHTR2A | |
| SCHEMBL7348188 | 0.89 | HTR1A (0.34) | SLC6A4HRH3SLC6A3DRD2SLC6A2 | |
| SCHEMBL7353677 | 0.89 | SLC6A4 (0.38) | SLC6A4HRH3SLC6A3DRD2SIGMAR1 | |
| SCHEMBL7346830 | 0.86 | SLC6A4 (0.39) | SLC6A4HRH3SLC6A3SLC6A2SIGMAR1 | |
| SCHEMBL7346562 | 0.85 | SLC6A4 (0.49) | SLC6A4HRH3SLC6A2HTR1AHTR2A | |
| SCHEMBL7350636 | 0.82 | POLB (0.33) | SLC6A4SLC6A3SLC6A2SIGMAR1HTR2A | |
| SCHEMBL7354019 | 0.82 | SLC6A4 (0.42) | SLC6A4HRH3SIGMAR1 | |
| SCHEMBL7354129 | 0.82 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7344633 | 0.82 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7351717 | 0.79 | CYP2D6 (0.34) | SLC6A4HRH3DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |