Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354019 | 0.91 | SLC6A4 (0.42) | SLC6A4HRH3SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL7353951 | 0.89 | HTR1A (0.33) | SLC6A4HRH3ALDH1A1TSHRSLC6A3 | |
| SCHEMBL7348954 | 0.88 | SLC6A4 (0.32) | SLC6A4HRH3SIGMAR1SLC6A3SLC6A2 | |
| SCHEMBL7346137 | 0.86 | SLC6A4 (0.39) | SLC6A4HRH3SIGMAR1SLC6A3SLC6A2 | |
| SCHEMBL7353677 | 0.84 | SLC6A4 (0.38) | SLC6A4HRH3SIGMAR1ALDH1A1SLC6A3 | |
| SCHEMBL7353033 | 0.82 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7346562 | 0.82 | SLC6A4 (0.49) | SLC6A4HRH3SLC6A2 | |
| SCHEMBL7356365 | 0.81 | POLB (0.34) | SLC6A4ALDH1A1SLC6A3SLC6A2HTT | |
| SCHEMBL7347814 | 0.81 | SLC6A4 (0.35) | SLC6A4HRH3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7357619 | 0.80 | SLC6A4 (0.35) | SLC6A4HRH3ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |